FRID - Fall Risk Increasing Drugs

Leader: Nathalie van der Velde

FOUNDED

September 2017

LINK WITH A SIG

SIG on Falls and Fracture and SIG on Pharmacology

OBJECTIVES

  • To update knowledge related to fall-risk-increasing drugs (FRIDs).
  • To successfully disseminate knowledge on FRIDs and FRIDs withdrawal to health care workers, students and the older population at risk and thus lessen the use of unnecessary FRIDs in older persons at risk.
  • To develop drug withdrawal interventions that are personalized and effective.
  • To harmonize practice on this topic across Europe.

OUTCOMES UNTIL 2020

Outcomes: Symposia

In 2017: Symposium on FRIDs at Dutch geriatric days, EU falls festival, EuGMS meeting, and Falls, frailty and bone health conference

In 2018: Symposium on FRIDs at EuGMS meeting

In 2019: Symposium on FRIDs at EuGMS meeting, and World Congress on Falls and Postural Stability

In 2020: Symposium on FRIDs at EuGMS online meeting:

‘TO TREAT OR NOT TO TREAT: DRUG- VERSUS DISEASE-RELATED FALL RISK’ 

(link to presentations)

1.      ANTIHYPERTENSIVE MEDICATION AND FALLS – GOOD, BAD OR “?” ? by Tomas Welsh

2.      DEPRESSION, ANTIDEPRESSANTS & FALL RISK: THERAPEUTIC DILEMMA’S by Nathalie van der Velde

3.      RISK OF FALLING – AN IMPACT OF PAIN AND USE OF ANALGETICS by Sirpa Hartikainen

        

Outcomes: Publications

Please see list below

Outcomes: Educational materials

A leaflet about FRIDs for public dissemination.

English:     

Dutch:     

Spanish:

Czech:

We encourage European countries to adopt and test the material, translating where necessary (Seppala et al. Drugs Aging 2019). Before doing so, please contact: Lotta Seppälä (l.j.seppala(at)amsterdamumc.nl)

PROJECTS, EVENTS IN 2021, 2022

Ongoing projects:

  • Preparation of working materials for knowledge dissemination for students and healthcare professionals
  • Online surveys on wishes and needs of doctors and patients regarding clinical decision support system communicating medication-related fall risk and current practice of medication management in older fallers

NEXT MEETING OF THE GROUP

EuGMS 2021 Congress in Athens, Greece

PUBLICATIONS

(Please also refer to Outcomes section of this page)

L.J. Seppala, M. Petrovic, J. Ryg, G. Bahat, E. Topinkova, K. Szczerbińska, T.J.M. van der Cammen, S. Hartikainen, B. Ilhan, F. Landi, Y. Morrissey, A. Mair, M. Gutiérrez-Valencia, M.H. Emmelot-Vonk, M.A. Caballero Mora, M. Denkinger, P. Crome, S.H.D. Jackson, A. Correa-Pérez, W. Knol, G. Soulis, A. Gudmundsson, G. Ziere, M. Wehling, D. O’Mahony, A. Cherubini, N. van der Velde. STOPPFall (Screening Tool of Older Persons Prescriptions in older adults with high fall risk): a Delphi study by the EuGMS Task and Finish Group on Fall-Risk-Increasing Drugs. Age and Ageing 2020; 1-11 doi: 10.1093/ageing/afaa249

Link to accompanying deprescribing tool for STOPPFalls: https://kik.amc.nl/falls/decision-tree/

Seppala LJ, van der Velde N, Masud T, Blain H, Petrovic M, van der Cammen TJ, Szczerbińska K, Hartikainen S, Kenny RA, Ryg J, Eklund P, Topinková E, Mair A, Laflamme L, Thaler H, Bahat G, Gutiérrez-Valencia M, Caballero-Mora MA, Landi F, Emmelot-Vonk MH; EuGMS Task and Finish Group on  Fall-Risk-Increasing Drugs, Cherubini A, Baeyens JP, Correa-Pérez A, Gudmundsson A, Marengoni A, O'Mahony D, Parekh N, Pisa FE, Rajkumar C, Wehling M, Ziere G; EuGMS Special Interest Group on Pharmacology. EuGMS Task and Finish group on Fall-Risk-Increasing Drugs (FRIDs): Position on Knowledge Dissemination, Management, and Future Research. Published in Drugs Aging. 2019 Apr;36(4):299-307 and Eur Geriatr Med (2019) 10: 275.

https://link.springer.com/article/10.1007%2Fs40266-018-0622-7

de Vries M, Seppala LJ, Daams JG, van de Glind EMM, Masud T, van der Velde N; EUGMS Task and Finish Group on Fall-Risk-Increasing Drugs. Fall-Risk-Increasing Drugs: A Systematic Review and Meta-Analysis: I. Cardiovascular Drugs. Published in J Am Med Dir Assoc. 2018 Apr;19(4):371.e1-371.e9.
https://www.jamda.com/article/S1525-8610(17)30698-9/abstract

Seppala LJ, Wermelink AMAT, de Vries M, Ploegmakers KJ, van de Glind EMM, Daams JG, van der Velde N; EUGMS task and Finish group on fall-risk-increasing drugs. Fall-Risk-Increasing Drugs: A Systematic Review and Meta-Analysis: II. Psychotropics. Published in J Am Med Dir Assoc. 2018 Apr;19(4):371.e11-371.e17.
https://www.jamda.com/article/S1525-8610(17)30784-3/abstract

Seppala LJ, van de Glind EMM, Daams JG, Ploegmakers KJ, de Vries M, Wermelink AMAT, van der Velde N; EUGMS Task and Finish Group on Fall-Risk-Increasing Drugs. Fall-Risk-Increasing Drugs: A Systematic Review and Meta-analysis: III. Others. Published in J Am Med Dir Assoc. 018 Apr;19(4):372.e1-372.e8.
https://www.jamda.com/article/S1525-8610(17)30785-5/abstract

GROUP MEMBERS

Austria: Heinrich Thaler

Belgium: Mirko Petrovic

Czech Republic: Eva Topinková

Denmark: Jesper Ryg

Finland: Sirpa Hartikainen

France: Hubert Blain, Jean Bousquet

Ireland: Irene O’Byrne-Maguire, Rose Anne Kenny

Italy: Francesco Landi

Netherlands: Tischa van der Cammen, Marielle Emmelot-Vonk, Nathalie van der Velde, Lotta Seppälä

Poland: Katarzyna Szczerbińska

Spain: Leocadio Rodriguez Mañas, Marta Gutiérrez-Valencia, Maria Angeles Caballero-Mora

Sweden: Lucie Laflamme, Gösta Bucht, Yngve Gustafsson, Olle Svensson, Patrik Eklund, Ulrika Pettersson-Kymmer

Turkey: Gulistan Bahat, Birkan Ilhat

UK: Tash Masud, Alpana Mair, Tomas Welsh, Yvonne Morrissey